Thyroid function after oropharyngeal, hypophariyngeal and laryngeal squamous cell carcinoma treatment

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Samanta Ruz G.
Hayo Breinbauer K.
Mariela Torrente A.

Keywords

Hypothyroidism, oropharyngeal, hypophariyngeal and laryngeal squamous cell carcinoma

Abstract

Introduction: Hypothyroidism is a complication of head and neck cancer treatment, it incidence goes from 7% to 57%. Aim: To estimate frequency of hipothyroidism in patients with cancer of pharynx and larynx and to dertermine factor of risk. Material and method: Transversal study. Thyroid function measurement in patients diagnosed and treated for oropharyngeal, hypophariyngeal and laryngeal squamous cell carcinoma at San Juan de Dios‘s Hospital since January 2006 to December 2007. Results: 55,5% presented an altered thyroid function after treatment. The treatment modality is crucial, on it‘s frequency, changing from 35 % with radiotherapy, v/s 83% when this one was associated with surgery. The chemotherapy did not show effects. Conclusions: The hypothyroidism is a frequent, but slightly recognized complication, which happens in more than 50 % of patients treated for for oropharyngeal, hypophariyngeal and laryngeal squamous cell carcinoma.

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