Role of the sentinel lymph node biopsy in the management of cutaneous squamous cell carcinoma in the head and neck

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Andres Quezada L.
Luis Molina D.
Mario Tapia C.
Cristóbal Araya Q.
Mauricio Chang S.
Fabio Valdes G.

Keywords

THRIVE, microlaryngeal surgery, apneic oxygenation, high-flow nasal oxygen, otorhinolaryngology

Abstract

Non-melanoma skin cancer is the most common cancer worldwide. Among them, cuta­neous squamous cell carcinoma (SCC) represents approximately 20% of cases, with an in­creasing incidence and greater impact on sun-exposed areas of the head and neck. While most cases are successfully treated with surgery, a subset of patients faces higher risks of recurrence, metastasis, and mortality. The presence of nodal metastasis significantly reduces survival, prompting the development of various management strategies for patients without clinical evidence of nodal involvement. These strategies include identifying high-risk groups, imaging evaluation, clinical observation, and elective cervical dissection. In recent years, the utility of sentinel lymph node biopsy (SLNB) has been investigated in managing SCC in the head and neck. However, there is insufficient evidence to establish its widespread use. This article reviews the current literature to assist head and neck surgical oncology teams in decision-making.

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